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In Treatment of Acne Clindex Gel is a combination medicine that helps treat acne (commonly called pimples) by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. The earlier you start using it, the less likely you are to get scars. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free. It should not be used if you have eczema or sunburned skin.